Osteoporosis isn’t just your grandma’s problem anymore.
It’s becoming a full-blown public health crisis, especially as people live longer and the global population keeps aging. Weak bones (aka low bone mineral density or BMD) lead to fractures. Fractures lead to hospital stays. And those hospital stays can turn into long-term disability—or worse.
The usual prescription? Eat well and move more. But here’s the million-dollar question: What if you’re trying to lose weight—say, to fight obesity or metabolic syndrome—but you’re also worried about keeping your bones strong?
That’s where things get tricky.
Weight Loss: Friend or Foe for Your Bones?
Losing weight is great for your heart, blood sugar, and knees. But it’s not always great for your skeleton. Especially if you’re over 60.
In fact, weight loss can sometimes accelerate bone loss—particularly in older adults. Even when you throw in exercise, many studies have shown that the pounds come off, but so does your bone mass.
So what gives?
Turns out, not all weight-loss strategies are created equal. And one specific combo might offer a sweet spot between shedding fat and not sacrificing your bones.
Enter: The Mediterranean Diet (Lite Version)
You’ve probably heard of the Mediterranean diet. It’s basically:
- Lots of veggies, fruits, nuts, and olive oil
- Whole grains > white bread
- Moderate fish and dairy
- Not much red meat or sweets
This diet has been linked to everything from a healthier heart to lower Alzheimer’s risk. But researchers wanted to know: Could it also help protect bone health in older adults trying to lose weight?
So they ran a huge clinical trial in Spain called PREDIMED-Plus.
The Study: Diet, Exercise, and 3 Years of Data
The researchers took a group of older adults with obesity and metabolic syndrome (aka the kind of people most likely to get osteoporosis and heart disease) and split them into two groups:
- Control group – They followed a regular Mediterranean diet (no calorie limits).
- Intervention group – They followed a reduced-calorie Mediterranean diet + physical activity + behavioral support.
Then they tracked their bone health over 3 years using fancy bone scans (DXA, for the nerds out there).
The Results: Bone Wins for the Mediterranean Makeover
Here’s what they found:
✅ Women in the intervention group kept more bone in their lower spine (lumbar area) than those in the control group.
✅ They also had better results in their hips and femurs—critical spots when it comes to preventing dangerous fractures.
✅ These benefits held up even when they excluded people taking calcium or vitamin D supplements (so it wasn’t just the pills helping out).
But here’s the fine print:
There was no major change in total body bone mass, and the effect wasn’t seen as clearly in men. Sorry guys.
Why Did Women Benefit More?
Blame (or thank) biology:
- Women naturally have more bone loss after menopause due to dropping estrogen.
- They also tend to carry more body fat, which affects bone density differently than it does in men.
- And the spine area (where the most benefit was seen) is a common weak point for postmenopausal women.
So this combo of diet + activity seemed to act like a safety net during weight loss—especially where women are most vulnerable.
So What Should You Actually Do?
Here’s the good news: You don’t need to be part of a Spanish clinical trial to benefit from these insights. If you’re over 50 and looking to lose weight without breaking yourself in the process, here’s a playbook:
-Follow a calorie-conscious Mediterranean-style diet
-Add regular physical activity—especially resistance training or walking
-Get some behavioral support—accountability works (think dietitians, group chats, or even an app)
-Talk to your doctor about bone scans, calcium & vitamin D needs
The Bottom Line
You can lose weight after 50 and still protect your bones—especially if you’re a woman.
This study shows that a smartly structured Mediterranean diet, combined with exercise and support, might slow down age-related bone loss and keep you stronger for longer.
Your bones might not be visible in your mirror selfies—but trust us, they’re worth taking care of.
Vázquez-Lorente H, García-Gavilán JF, Shyam S, Konieczna J, Martínez JA, Martín-Sánchez V, Fitó M, Ruiz-Canela M, Paz-Graniel I, Curto A, Martinez-Urbistondo D, de Paz Fernández JA, Romaguera D, Babio N, Salas-Salvadó J. Mediterranean Diet, Physical Activity, and Bone Health in Older Adults: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2025 Apr 1;8(4):e253710. doi: 10.1001/jamanetworkopen.2025.3710. PMID: 40198072; PMCID: PMC11979728.
